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Karyopharm Therapeutics
Karyopharm Therapeutics
(KPTI)
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Xpovio
Selinexor
2019-07-03
2032-2035
Multiple myeloma
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Selinexor
neoplasm metastasis
,
biphenotypic leukemia acute
,
precursor cell lymphoblastic leukemia-lymphoma
,
hematologic neoplasms
,
renal cell carcinoma
,
fallopian tube neoplasms
,
skin neoplasms
,
cutaneous malignant melanoma
,
rectal neoplasms
,
aggression
,
ewing sarcoma
,
stomach neoplasms
,
esophageal neoplasms
,
gliosarcoma
,
chromosome aberrations
,
b-cell chronic lymphocytic leukemia
,
prolymphocytic leukemia
,
lymphoid leukemia
,
bcr-abl positive chronic myelogenous leukemia
,
leiomyosarcoma
,
endometrial stromal sarcoma
,
hodgkin disease
,
brain neoplasms
,
nervous system neoplasms
,
immunoglobulin light-chain amyloidosis
,
amyloidosis
,
hepatocellular carcinoma
,
liver neoplasms
,
phenylketonurias
,
hematopoietic stem cell transplantation
,
sarcoma
,
non-hodgkin lymphoma
,
t-cell lymphoma
,
t-cell lymphoma peripheral
,
myelodysplastic syndromes
,
glioblastoma
,
carcinoma
,
ovarian neoplasms
,
neurofibrosarcoma
,
central nervous system neoplasms
,
preleukemia
,
syndrome
,
breast neoplasms
,
non-small-cell lung carcinoma
,
triple negative breast neoplasms
,
lung neoplasms
,
melanoma
,
colorectal neoplasms
,
nerve sheath neoplasms
,
extranodal nk-t-cell lymphoma
,
glioma
,
small cell lung carcinoma
,
squamous cell neoplasms
,
alveolar soft part sarcoma
,
adenocarcinoma
,
pancreatic ductal carcinoma
,
prostatic neoplasms
,
coronavirus infections
,
thymoma
,
glandular and epithelial neoplasms
,
thymus neoplasms
,
rhabdoid tumor
,
thrombocytopenia
,
myoepithelioma
,
drug-related side effects and adverse reactions
,
gastrointestinal stromal tumors
,
maximum tolerated dose
,
recreational drug use
,
pancreatic neoplasms
,
acinar cell carcinoma
,
essential thrombocythemia
,
polycythemia vera
,
thrombocytosis
,
polycythemia
,
squamous cell carcinoma
,
b-cell lymphoma marginal zone
,
follicular lymphoma
,
waldenstrom macroglobulinemia
,
urologic neoplasms
,
transitional cell carcinoma
,
infections
,
communicable diseases
,
diabetic foot
,
ulcer
,
foot ulcer
,
t-cell lymphoma cutaneous
,
neuroendocrine carcinoma
,
uterine cervical neoplasms
,
smoldering multiple myeloma
,
residual neoplasm
,
ovarian epithelial carcinoma
,
wilms tumor
,
osteosarcoma
,
clear cell sarcoma
,
fibrosarcoma
,
solitary fibrous tumors
,
hemangiosarcoma
,
epithelioid hemangioendothelioma
,
myxoid liposarcoma
,
benign fibrous histiocytoma
,
vascular neoplasms
,
glomus tumor
,
disorders of sex development
,
dermatofibrosarcoma
,
adipose tissue neoplasms
,
smooth muscle tumor
,
plasma cell granuloma
,
granular cell tumor
,
ductal carcinoma
,
myelomonocytic leukemia chronic
,
myelomonocytic leukemia juvenile
,
multiple myeloma
,
plasma cell neoplasms
,
myeloid leukemia acute
,
recurrence
,
neoplasms
,
leukemia
,
myeloid leukemia
,
primary myelofibrosis
,
endometrial neoplasms
,
liposarcoma
,
covid-19
,
virus diseases
,
myeloproliferative disorders
,
epstein-barr virus infections
,
hemophagocytic lymphohistiocytosis
,
lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
mantle-cell lymphoma
,
salivary gland neoplasms
,
mothers
Belantamab
renal insufficiency
,
autoimmune diseases
,
recurrence
,
neoplasms
,
corneal diseases
,
immunoglobulin light-chain amyloidosis
,
hematologic diseases
,
blood protein disorders
,
paraproteinemias
,
amyloidosis
,
large-cell lymphoma anaplastic
,
plasmablastic lymphoma
,
thrombocytopenic purpura idiopathic
,
thrombocytopenia
,
multiple myeloma
,
plasma cell neoplasms
,
sepsis
,
agranulocytosis
,
opportunistic infections
Mafodotin
multiple myeloma
,
plasma cell neoplasms
Docusate
asthma
,
bipolar disorder
,
heart failure
,
type 2 diabetes mellitus
,
diabetes mellitus
,
multiple myeloma
,
plasma cell neoplasms
,
malaria
,
falciparum malaria
,
streptococcal infections
,
human influenza
,
infections
,
hiv infections
,
acquired immunodeficiency syndrome
,
migraine disorders
,
skin care
Benzimidazole
non-hodgkin lymphoma
,
ulcerative colitis
,
crohn disease
,
colitis
,
ulcer
,
psoriasis
,
rheumatoid arthritis
,
arthritis
,
pharmacokinetics
,
neoplasms
,
multiple myeloma
,
plasma cell neoplasms
,
glioblastoma
,
glioma
,
gliosarcoma
,
astrocytoma
,
diffuse intrinsic pontine glioma
,
optic nerve glioma
,
brain stem neoplasms
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
syndrome
,
healthy volunteers/patients
,
lymphoma
,
peptic esophagitis
,
peripheral arterial disease
,
b-cell lymphoma marginal zone
,
follicular lymphoma
,
mantle-cell lymphoma
,
leukemia
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
infections
,
communicable diseases
,
helminthiasis
,
vomiting
,
gastroenteritis
,
heartburn
,
non-erosive reflux disease
,
asthma
,
gastroesophageal reflux
,
sleep initiation and maintenance disorders
,
sleep wake disorders
,
parasomnias
,
atrial fibrillation
,
venous thromboembolism
,
thromboembolism
,
stroke
,
schizophrenia
,
sudden death cardiac
,
death
,
sudden death
Cilmostim
neoplasms
,
lung neoplasms
,
small cell lung carcinoma
,
myeloid leukemia acute
,
colorectal neoplasms
,
ovarian neoplasms
,
triple negative breast neoplasms
,
biliary tract neoplasms
,
follicular lymphoma
,
hiv infections
,
non-small-cell lung carcinoma
,
large b-cell lymphoma diffuse
,
cytomegalovirus retinitis
,
retinitis
,
non-hodgkin lymphoma
,
acquired immunodeficiency syndrome
,
infections
Enoblituzumab
allergic rhinitis
,
rhinitis
,
allergic rhinitis seasonal
,
actinic keratosis
,
keratosis
Aglatimagene besadenovec
breast neoplasms
,
ovarian neoplasms
,
ovarian epithelial carcinoma
,
neoplasms
,
lung neoplasms
,
glioblastoma
,
small cell lung carcinoma
,
neuroendocrine carcinoma
,
prostatic neoplasms
,
castration-resistant prostatic neoplasms
,
adenocarcinoma
,
head and neck neoplasms
,
esophageal neoplasms
,
gastrointestinal neoplasms
,
sarcoma
,
urogenital neoplasms
,
skin neoplasms
,
melanoma
,
colonic neoplasms
,
healthy volunteers/patients
Lenograstim
neoplasms
,
hodgkin disease
,
myelodysplastic syndromes
,
neutropenia
,
chemotherapy-induced febrile neutropenia
,
healthy volunteers/patients
Edrecolomab
non-hodgkin lymphoma
,
b-cell lymphoma
Calcium dobesilate
multiple myeloma
Phenylalanine
phenylketonurias
,
behavior and behavior mechanisms
Doconexent
melanoma
,
healthy volunteers/patients
,
prostatic neoplasms
,
renal cell carcinoma
,
breast neoplasms
,
ovarian neoplasms
,
pancreatic neoplasms
,
neoplasms
,
postmenopausal osteoporosis
,
head and neck neoplasms
,
colorectal neoplasms
,
stomach neoplasms
,
adenocarcinoma
,
obesity
,
overweight
,
adenocarcinoma of lung
,
bronchiolo-alveolar adenocarcinoma
,
squamous cell carcinoma of head and neck
,
mantle-cell lymphoma
,
lung neoplasms
,
non-small-cell lung carcinoma
,
major depressive disorder
,
lymphoma
,
hodgkin disease
,
schizophrenia
,
osteoporosis
Lornoxicam
t-cell lymphoma
,
t-cell lymphoma peripheral
,
lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
breast neoplasms
,
peripheral nervous system diseases
Molgramostim
multiple myeloma
,
recurrence
,
brain neoplasms
,
neoplasms
,
glioblastoma
,
neuroblastoma
,
glioma
,
central nervous system neoplasms
,
germ cell and embryonal neoplasms
,
medulloblastoma
,
follicular lymphoma
,
rhabdoid tumor
,
meningioma
,
ependymoma
,
astrocytoma
,
choroid plexus neoplasms
,
oligodendroglioma
,
primitive neuroectodermal tumors
,
ganglioglioma
,
pinealoma
,
neuroepithelial neoplasms
,
hypertrophic pyloric stenosis
,
ganglioneuroblastoma
,
phenylketonurias
,
breast neoplasms
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoma
,
lymphoid leukemia
,
blast crisis
,
prostatic neoplasms
,
mantle-cell lymphoma
,
hodgkin disease
,
pancreatic neoplasms
,
triple negative breast neoplasms
,
endometrial neoplasms
,
melanoma
,
non-hodgkin lymphoma
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
leukemia
,
myeloid leukemia acute
,
bcr-abl positive chronic myelogenous leukemia
,
myeloid leukemia
,
myeloid leukemia chronic-phase
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