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Company ReportsKaryopharm Therapeutics

Karyopharm Therapeutics(KPTI)

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Therapeutic Areas:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Xpovio	Selinexor	2019-07-03	2032-2035	Multiple myeloma

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

neoplasm metastasis

,

precursor cell lymphoblastic leukemia-lymphoma

,

hematologic neoplasms

,

lymphoid leukemia

,

renal cell carcinoma

,

fallopian tube neoplasms

,

,

cutaneous malignant melanoma

,

rectal neoplasms

,

,

,

stomach neoplasms

,

esophageal neoplasms

,

,

b-cell chronic lymphocytic leukemia

,

prolymphocytic leukemia

,

biphenotypic leukemia acute

,

bcr-abl positive chronic myelogenous leukemia

,

,

,

endometrial stromal sarcoma

,

hodgkin disease

,

brain neoplasms

,

nervous system neoplasms

,

,

immunoglobulin light-chain amyloidosis

,

hepatocellular carcinoma

,

liver neoplasms

,

phenylketonurias

,

hematopoietic stem cell transplantation

,

,

,

non-hodgkin lymphoma

,

t-cell lymphoma

,

,

t-cell lymphoma peripheral

,

myelodysplastic syndromes

,

,

,

,

ovarian neoplasms

,

breast neoplasms

,

non-small-cell lung carcinoma

,

triple negative breast neoplasms

,

,

colorectal neoplasms

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

,

,

small cell lung carcinoma

,

central nervous system neoplasms

,

squamous cell neoplasms

,

alveolar soft part sarcoma

,

pancreatic ductal carcinoma

,

prostatic neoplasms

,

mantle-cell lymphoma

,

,

coronavirus infections

,

,

glandular and epithelial neoplasms

,

thymus neoplasms

,

,

,

thrombocytopenia

,

,

drug-related side effects and adverse reactions

,

gastrointestinal stromal tumors

,

maximum tolerated dose

,

recreational drug use

,

pancreatic neoplasms

,

acinar cell carcinoma

,

essential thrombocythemia

,

polycythemia vera

,

,

,

squamous cell carcinoma

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

waldenstrom macroglobulinemia

,

urologic neoplasms

,

transitional cell carcinoma

,

,

communicable diseases

,

,

,

,

t-cell lymphoma cutaneous

,

neuroendocrine carcinoma

,

uterine cervical neoplasms

,

smoldering multiple myeloma

,

ovarian epithelial carcinoma

,

,

,

hemangiosarcoma

,

benign fibrous histiocytoma

,

,

extranodal nk-t-cell lymphoma

,

ductal carcinoma

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

multiple myeloma

,

plasma cell neoplasms

,

myeloid leukemia acute

,

,

myeloid leukemia

,

,

,

primary myelofibrosis

,

endometrial neoplasms

,

,

,

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

salivary gland neoplasms

multiple myeloma

,

plasma cell neoplasms

agammaglobulinemia

,

alzheimer disease

,

immunologic deficiency syndromes

,

primary immunodeficiency diseases

ovarian neoplasms

,

ovarian epithelial carcinoma

Aglatimagene besadenovec

prostatic neoplasms

,

mycobacterium infections

,

non-hodgkin lymphoma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

Calcium dobesilate

colorectal neoplasms

,

head and neck neoplasms

,

squamous cell carcinoma

,

squamous cell neoplasms

,

non-small-cell lung carcinoma

,

,

multiple myeloma

,

plasma cell neoplasms

,

neoplasm metastasis

,

esophageal neoplasms

,

neoplasm metastasis

,

hepatocellular carcinoma

,

liver neoplasms

,

healthy volunteers/patients

,

,

multiple myeloma

,

,

squamous cell carcinoma

,

plasma cell neoplasms

,

colorectal neoplasms

,

head and neck neoplasms

,

squamous cell carcinoma of head and neck

,

rectal neoplasms

,

non-hodgkin lymphoma

,

,

synovial sarcoma

,

,

,

sezary syndrome

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

urologic neoplasms

,

urogenital neoplasms

,

penile neoplasms

,

male urogenital diseases

,

urogenital diseases

,

,

non-small-cell lung carcinoma

,

,

breast neoplasms

,

,

,

urinary bladder neoplasms

,

triple negative breast neoplasms

,

giant cell arteritis

,

polymyalgia rheumatica

,

ulcerative colitis

,

,

,

ankylosing spondylitis

,

spondylarthritis

,

,

rheumatoid arthritis

,

,

ovarian neoplasms

,

fallopian tube neoplasms

,

ovarian epithelial carcinoma

,

uterine cervical neoplasms

,

,

cardiovascular diseases

,

hyperlipidemias

,

familial combined hyperlipidemia

,

hyperlipoproteinemias

cerebrotendinous xanthomatosis

,

,

alagille syndrome

,

,

,

substance withdrawal syndrome

,

intrahepatic cholestasis

,

cerebrotendinous xanthomatosis

,

healthy volunteers/patients

,

hepatic insufficiency

,

ovarian epithelial carcinoma

,

castration-resistant prostatic neoplasms

,

myeloid leukemia acute

,

myeloid leukemia

,

,

uveal neoplasms

,

,

,

huntington disease

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

hiv seropositivity

,

,

central nervous system neoplasms

,

mantle-cell lymphoma

,

non-hodgkin lymphoma

,

uterine cervical neoplasms

,

plasma cell neoplasms

,

salivary gland neoplasms

,

cholangiocarcinoma

,

neuroendocrine tumors

,

,

chronic hepatitis b

,

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

unknown primary neoplasms

,

lobular carcinoma

,

invasive hydatidiform mole

,

,

coronary artery disease

,

myocardial ischemia

,

gastrointestinal neoplasms

,

respiratory tract diseases

,

digestive system neoplasms

,

gastrointestinal diseases

,

respiratory tract neoplasms

,

bronchogenic carcinoma

,

thoracic neoplasms

,

intestinal neoplasms

,

digestive system diseases

,

colonic diseases

,

intestinal diseases

,

bronchial neoplasms

,

waldenstrom macroglobulinemia

,

follicular lymphoma

,

myelodysplastic syndromes

,

,

,

,

uterine neoplasms

,

female genital neoplasms

,

bronchiolo-alveolar adenocarcinoma

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

,

breast neoplasms

,

,

colorectal neoplasms

,

,

triple negative breast neoplasms

,

hepatocellular carcinoma

,

liver neoplasms

,

renal cell carcinoma

,

,

ovarian neoplasms

,

neoplasm metastasis

,

brain neoplasms

,

b-cell chronic lymphocytic leukemia

,

head and neck neoplasms

,

lymphoid leukemia

,

hematologic neoplasms

,

prostatic neoplasms

,

multiple myeloma

,

thyroid neoplasms

,

papillary thyroid cancer

,

large-cell lymphoma anaplastic

,

neoplasms by site

,

,

thyroid diseases

,

lymphoproliferative disorders

,

neoplasms by histologic type

,

malignant mesothelioma

,

,

,

anaplastic thyroid carcinoma

,

laryngeal neoplasms

,

erdheim-chester disease

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

inflammatory breast neoplasms

,

kidney transplantation

,

bcr-abl positive chronic myelogenous leukemia

,

non-small-cell lung carcinoma

,

,

,

,

pancreatic neoplasms

,

,

communicable diseases

,

,

acquired immunodeficiency syndrome

,

disease progression

,

adenocarcinoma of lung

,

kidney diseases

,

polyomavirus infections

,

liver cirrhosis

,

,

,

renal insufficiency

,

acute kidney injury

,

,

endometrial neoplasms

,

uterine hemorrhage

,

,

,

alzheimer disease

,

frontotemporal dementia

,

progressive supranuclear palsy

,

primary progressive aphasia

,

pick disease of the brain

,

hodgkin disease

,

myeloid leukemia

,

myelodysplastic syndromes

,

,

myeloid leukemia acute

,

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

colorectal neoplasms

,

multiple myeloma

,

plasma cell neoplasms

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