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Company ReportsKaryopharm Therapeutics

Karyopharm Therapeutics(KPTI)

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Clinical Trials

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Therapeutic Areas:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Xpovio	Selinexor	2019-07-03	2032-2035	Multiple myeloma

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

neoplasm metastasis

,

biphenotypic leukemia acute

,

precursor cell lymphoblastic leukemia-lymphoma

,

hematologic neoplasms

,

renal cell carcinoma

,

fallopian tube neoplasms

,

,

cutaneous malignant melanoma

,

rectal neoplasms

,

,

,

stomach neoplasms

,

esophageal neoplasms

,

,

chromosome aberrations

,

b-cell chronic lymphocytic leukemia

,

prolymphocytic leukemia

,

lymphoid leukemia

,

bcr-abl positive chronic myelogenous leukemia

,

endometrial stromal sarcoma

,

hodgkin disease

,

brain neoplasms

,

nervous system neoplasms

,

immunoglobulin light-chain amyloidosis

,

,

hepatocellular carcinoma

,

liver neoplasms

,

phenylketonurias

,

hematopoietic stem cell transplantation

,

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

myelodysplastic syndromes

,

,

non-hodgkin lymphoma

,

,

ovarian neoplasms

,

neurofibrosarcoma

,

extranodal nk-t-cell lymphoma

,

central nervous system neoplasms

,

,

,

breast neoplasms

,

non-small-cell lung carcinoma

,

triple negative breast neoplasms

,

,

,

colorectal neoplasms

,

nerve sheath neoplasms

,

,

glandular and epithelial neoplasms

,

small cell lung carcinoma

,

thrombocytopenia

,

squamous cell neoplasms

,

alveolar soft part sarcoma

,

,

pancreatic ductal carcinoma

,

prostatic neoplasms

,

,

coronavirus infections

,

,

thymus neoplasms

,

,

,

drug-related side effects and adverse reactions

,

gastrointestinal stromal tumors

,

maximum tolerated dose

,

recreational drug use

,

pancreatic neoplasms

,

acinar cell carcinoma

,

squamous cell carcinoma

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

waldenstrom macroglobulinemia

,

urologic neoplasms

,

transitional cell carcinoma

,

,

communicable diseases

,

,

,

,

t-cell lymphoma cutaneous

,

neuroendocrine carcinoma

,

uterine cervical neoplasms

,

smoldering multiple myeloma

,

residual neoplasm

,

ovarian epithelial carcinoma

,

,

,

,

clear cell sarcoma

,

,

hemangiosarcoma

,

epithelioid hemangioendothelioma

,

synovial sarcoma

,

myxoid liposarcoma

,

benign fibrous histiocytoma

,

,

disorders of sex development

,

dermatofibrosarcoma

,

adipose tissue neoplasms

,

granular cell tumor

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

,

refractory anemia with excess of blasts

,

multiple myeloma

,

plasma cell neoplasms

,

myeloid leukemia acute

,

,

,

,

myeloid leukemia

,

primary myelofibrosis

,

endometrial neoplasms

,

,

,

myeloproliferative disorders

,

,

uterine neoplasms

,

neoplasms by site

,

uterine diseases

,

genital diseases

,

epstein-barr virus infections

,

hemophagocytic lymphohistiocytosis

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

mantle-cell lymphoma

,

salivary gland neoplasms

,

,

myeloid sarcoma

multiple myeloma

,

plasma cell neoplasms

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

triple negative breast neoplasms

,

squamous cell carcinoma of head and neck

,

multiple myeloma

,

plasma cell neoplasms

,

,

follicular lymphoma

,

,

brain neoplasms

,

,

bipolar disorder

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

multiple myeloma

,

plasma cell neoplasms

,

,

falciparum malaria

,

streptococcal infections

,

human influenza

,

,

,

acquired immunodeficiency syndrome

,

migraine disorders

,

,

non-alcoholic fatty liver disease

,

,

psoriatic arthritis

,

,

alzheimer disease

,

,

hepatic insufficiency

,

,

insulin resistance

,

,

acute coronary syndrome

,

cardiac catheterization

,

heart valve prosthesis

,

venous thrombosis

,

systolic murmurs

,

polycystic kidney diseases

,

chronic renal insufficiency

,

chronic kidney failure

,

secondary prevention

,

neoplasm metastasis

,

replacement arthroplasty knee

,

,

,

disease progression

,

,

percutaneous coronary intervention

,

replacement arthroplasty hip

,

intracranial sinus thrombosis

,

healthy volunteers/patients

,

,

atrial fibrillation

,

thromboembolism

,

venous thromboembolism

,

essential hypertension

,

renal insufficiency

,

kidney diseases

,

,

,

cardiovascular diseases

,

isolated systolic hypertension

,

coronary artery disease

,

myocardial ischemia

,

diabetic nephropathies

,

coronary disease

,

arteriosclerosis

,

type 2 diabetes mellitus

,

diabetes mellitus

,

metabolic syndrome

,

heart valve diseases

,

replacement arthroplasty

,

cognitive dysfunction

,

,

,

,

,

cerebral infarction

,

myocardial infarction

,

,

,

,

cognition disorders

,

,

,

,

transient ischemic attack

,

,

liver cirrhosis

,

,

rheumatoid arthritis

,

Aglatimagene besadenovec

prostatic neoplasms

colorectal neoplasms

,

neoplasm metastasis

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

non-hodgkin lymphoma

,

multiple myeloma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

b-cell chronic lymphocytic leukemia

,

bcr-abl positive chronic myelogenous leukemia

,

hodgkin disease

,

t-cell lymphoma peripheral

,

myeloid leukemia

,

lymphoid leukemia

non-hodgkin lymphoma

,

b-cell lymphoma

Calcium dobesilate

,

hematologic neoplasms

,

non-hodgkin lymphoma

,

,

hodgkin disease

phenylketonurias

,

behavior and behavior mechanisms

,

restless legs syndrome

,

psychomotor agitation

,

,

myocardial infarction

,

uterine cervical neoplasms

,

,

hematologic diseases

,

blood protein disorders

,

plasma cell neoplasms

,

paraproteinemias

,

corneal diseases

,

drug resistance

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

synovial sarcoma

,

falciparum malaria

,

heat stress disorders

,

,

combat disorders

,

traumatic stress disorders

,

,

healthy volunteers/patients

,

,

focal segmental glomerulosclerosis

,

sickle cell anemia

,

beta-thalassemia

,

,

sickle cell trait

,

,

human influenza

,

influenza in birds

,

multiple myeloma

,

cardiovascular diseases

,

breast neoplasms

,

,

rheumatoid arthritis

,

,

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

inflammatory breast neoplasms

,

,

,

glucose metabolism disorders

,

metabolic diseases

,

diabetes mellitus

,

vascular diseases

,

,

metabolic syndrome

,

endocrine system diseases

,

hypertriglyceridemia

,

,

atrial fibrillation

,

,

tick-borne encephalitis

,

,

,

,

mitochondrial diseases

,

mitral valve insufficiency

,

,

,

non-alcoholic fatty liver disease

,

,

wasting syndrome

,

,

,

,

,

cytomegalovirus infections

,

communicable diseases

,

gastrointestinal diseases

,

digestive system diseases

,

depressive disorder

hodgkin disease

,

mantle-cell lymphoma

,

multiple myeloma

,

prolymphocytic leukemia t-cell

,

plasma cell leukemia

,

,

non-hodgkin lymphoma

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

myeloproliferative disorders

,

primary myelofibrosis

,

b-cell chronic lymphocytic leukemia

,

refractory anemia with excess of blasts

,

myelodysplastic syndromes

,

myelomonocytic leukemia chronic

,

hematologic neoplasms

,

bcr-abl positive chronic myelogenous leukemia

,

burkitt lymphoma

,

,

b-cell lymphoma

,

ovarian neoplasms

,

fallopian tube neoplasms

,

myeloid leukemia acute

,

breast neoplasms

,

triple negative breast neoplasms

,

inflammatory breast neoplasms

,

philadelphia chromosome

,

hematologic diseases

,

,

ovarian epithelial carcinoma

,

peritoneal neoplasms

,

,

pancreatic neoplasms

,

prolymphocytic leukemia

,

b-cell leukemia

,

myelodysplastic-myeloproliferative diseases

,

hematopoietic stem cell transplantation

,

sickle cell anemia

,

graft rejection

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

graft vs host disease

,

,

large b-cell lymphoma diffuse

,

bronchiolitis obliterans syndrome

multiple myeloma

,

,

brain neoplasms

,

,

,

,

,

central nervous system neoplasms

,

germ cell and embryonal neoplasms

,

medulloblastoma

,

follicular lymphoma

,

,

,

,

,

choroid plexus neoplasms

,

oligodendroglioma

,

primitive neuroectodermal tumors

,

,

,

neuroepithelial neoplasms

,

hypertrophic pyloric stenosis

,

ganglioneuroblastoma

,

phenylketonurias

,

breast neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

lymphoid leukemia

,

,

prostatic neoplasms

,

mantle-cell lymphoma

,

hodgkin disease

,

pancreatic neoplasms

,

triple negative breast neoplasms

,

endometrial neoplasms

,

,

non-hodgkin lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

myeloid leukemia acute

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

myeloid leukemia chronic-phase

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